Table 1.
Genetic correlations among PFA phenotypes, von Willebrand factor, coagulation factor VIII and ABO genotype.
Phenotype | Col-Epi | VWF | FVIII | ABO |
---|---|---|---|---|
Col-ADP | ρ = 0.7917 (5.80 × 10−9) | ρ = −0.7002 (1.02 × 10−10) | ρ = −0.6209 (2.66 × 10−8) | ρ = 0.5895 (7.01 × 10−9) |
Col-Epi | - | ρ = −0.6342 (7.14 × 10−8) | ρ = −0.5947 (3.97 × 10−7) | ρ = 0.4477 (0.0003) |
ρ = genetic correlation and p-value (in brackets); VWF = von Willebrand factor antigen; FVIII = coagulation factor VIII activity; ABO = ABO genotype, considering dominant effect of allele O.