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Representative multiple reaction monitoring (MRM) chromatograms of blank cell lysates (a), blank cell lysates spiked with standard solutions (b), and cell lysates collected after coincubation with Chelidonium majus for 10 min (c). Peak 1: protopine; 2: chelidonine; 3: coptisine; 4: palmatine (internal standard, IS); 5 sanguinarine; 6: chelerythrine.
