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. 2019 Jul 8;20(13):3352. doi: 10.3390/ijms20133352

Figure 2.

Figure 2

Projected LOD cumulative incidence and lifetime risk increase for life expectancy increases of 5, 10, and 15 years (baseline without gene therapy). (A) Alzheimer’s disease, (B) type 2 diabetes, (C) cerebral stroke, (D) coronary artery disease, (E) breast cancer, (F) prostate cancer, (G) colorectal cancer, and (H) lung cancer. This is the baseline scenario, without gene therapy or other health improvements for the plotted LOD. It represents the case where life expectancy increases due to causes other than the plotted LOD. Lifetime risk (lifetime cumulative incidence) corresponds to the lifetime (rightmost) values of the plots.