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. 2019 Jul 2;20(13):3241. doi: 10.3390/ijms20133241

Figure 2.

Figure 2

Phytosterols are anti-proliferative in breast cancer cell cultures. The anti-proliferative effects of STIG, SITO, CAMP, BRASS and STIG over 48 h was assessed by MTT in (a) MDA-MB-468, (b) MDA-MB-231, and (c) MCF7 cells. Cell viability relative to vehicle control was measured after treating with plant sterols and stanols (PSSs) at indicated concentrations. Data are presented as mean of three independent replicates (open circles) with SEM. For assessing changes between individual concentrations and vehicle, one-way ANOVA with Holm-Sidak correction for multiple testing and post-test for linear trend was performed. Significance levels are indicated by € = p < 0.05 and # = p < 0.0001. Linear trend was significant for all PSS in all cell lines except for BRAS in MCF7 (ns).