Table 2.
HPV detection between HPV DNA Array and Cobas, stratified by age, histology, and cytology
| Cobas | |||||||
|---|---|---|---|---|---|---|---|
| HPV DNA Array | Positive | Negative | Agreement | Kappa | Interpretationa | McNemar’s p | |
| Overall population (499) | Positive | 329 | 2 | 81.4% | 0.613 | good | 0.000 |
| Negative | 75 | 93 | |||||
| < 30 (217)b | Positive | 163 | 0 | 86.2% | 0.618 | good | 0.000 |
| Negative | 26 | 28 | |||||
| ≥30 (276) b | Positive | 164 | 2 | 77.4% | 0.593 | moderate | 0.000 |
| Negative | 48 | 62 | |||||
| CIN2+ (22) | Positive | 22 | 0 | 100% | |||
| Negative | 0 | 0 | |||||
| HGSIL (8) | Positive | 8 | 0 | 100% | |||
| Negative | 0 | 0 | |||||
aInterpretation values: poor (< 0.20), fair (0.21–0.40), moderate (0.41–0.60), good (0.61–0.80), very good (0.81–1.00)
b6 samples, for which the age information was unavailable, were excluded from the analysis