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. 2019 Jul 23;19:658. doi: 10.1186/s12879-019-4289-4

Table 3.

Predictive values of Pj PCR and betaglucan in serum at a pre-test probability of 20%

Index tests in serum Positive predictive value Negative predictive value
Pj PCR positive 0.46 1.0
Pj PCR with Ct ≤34a 0.71 0.99
BG ≥80 pg/mlb 0.45 0.99
BG ≥200 pg/mlb 0.63 0.98
BG ≥400 pg/mlb 0.69 0.97
Pj PCR positive and BG ≥200 pg/mlb 0.70 0.98

Pj Pneumocystis jirovecii, PCP Pneumocystis jirovecii pneumonia, BG 1,3-ß-D-glucan

The results are based on 26 patients with PCP and 21 HIV-infected negative controls

aThree PCP patients whose serum samples had been analysed after 1:2 dilution were excluded

bOne PCP patient whose serum sample was not analyzed for BG due to insufficient volume of serum was excluded