Table 3.
Predictive values of Pj PCR and betaglucan in serum at a pre-test probability of 20%
| Index tests in serum | Positive predictive value | Negative predictive value |
|---|---|---|
| Pj PCR positive | 0.46 | 1.0 |
| Pj PCR with Ct ≤34a | 0.71 | 0.99 |
| BG ≥80 pg/mlb | 0.45 | 0.99 |
| BG ≥200 pg/mlb | 0.63 | 0.98 |
| BG ≥400 pg/mlb | 0.69 | 0.97 |
| Pj PCR positive and BG ≥200 pg/mlb | 0.70 | 0.98 |
Pj Pneumocystis jirovecii, PCP Pneumocystis jirovecii pneumonia, BG 1,3-ß-D-glucan
The results are based on 26 patients with PCP and 21 HIV-infected negative controls
aThree PCP patients whose serum samples had been analysed after 1:2 dilution were excluded
bOne PCP patient whose serum sample was not analyzed for BG due to insufficient volume of serum was excluded