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. 2019 Jul 23;19:658. doi: 10.1186/s12879-019-4289-4

Table 4.

HIV-infected control patients with positive Pj PCR in serum

Pat CD4 cell count (cells/uL) Criteria of the PCP reference standard of this study Outcome Index tests
Respiratory symptoms Radiologic findings Hypoxia Pj analysis respiratory specimen TMP-SMX Other lung infection BG (pg/ml) Pj PCR in serum Ct value
1 100 Dry cough Unknown Unknown Unknown No No Survival > 2000 32
2 30 Dry cough Discrete interstitial opacity Unknown Unknown Prophylaxis dose No Survival 807 33
3 10 Dry cough Normal Unknown Unknown Nob No Survival < 50 39
4 80 Dyspnea Discrete GGO Unknown PCR nega No No Survival 60 38
5 50 Productive cough and dyspnea Normal No PCR posa Prophylaxis dose No Survival 177 42
6 50 No Normal No Unknown No No Survival < 50 39

PCP Pneumocystis jirovecii pneumonia, Pj Pneumocystis jirovecii, TMP-SMX trimethoprim–sulfamethoxazole, BG 1,3-ß-D-glucan, Ct Cycle threshold, GGO ground glass opacity

For patients where Pj analysis, radiological exam or measurement of SpO2 was not performed, the data is noted as unknown

aPCR on sputum samples

breceived treatment for toxoplasmosis with pyrimethamine and sulphonamide