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. 2019 Jul 23;18:79. doi: 10.1186/s12938-019-0700-z

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Modulating the neuronal firing in downstream region by stimulations of Schaffer collaterals. a An example of a pulse train (0.5 s) with a lower frequency of 20 Hz. Top to bottom: raw recording, MUA signal, raster plot of unit spikes, and a segment of expanded MUA signal. b Neuronal firing induced by pulse trains (0.5 s) with a higher frequency of 100 Hz. Top (4 rows): a typical sweep of stimulation. Bottom: dynamic changes of the mean firing rate of MUA calculated from 10 sweeps of identical stimulations. The red bars or the shadow area in plots denotes the stimulation period. The dashed lines with a “▼” in the expanded signals denote removed stimulation artifacts