Table 2.
Associations of circulating heparan sulfate with plasma indices of endothelial injury, coagulation, and inflammation (ProCESS cohort, 6 h after enrollment)
| Marker | Pearson r | p-value | Number of subjects analyzed |
|---|---|---|---|
| Endothelial Injury/Activation | |||
| sFLT-1 (soluble VEGF-receptor 1) | 0.4097 | 0.0017 | 56 |
| Angiopoietin-2 | 0.2367 | 0.0790 | 56 |
| Inflammation | |||
| Tumor necrosis factor-α | 0.2325 | 0.1384 | 42 |
| Interleukin-6 | 0.3537 | 0.0216 | 42 |
| Coagulation | |||
| Tissue plasminogen activator | 0.3356 | 0.0114 | 56 |
| D-dimer | 0.0926 | 0.5699 | 40 |
| Thrombomodulin | 0.4997 | <0.0001 | 56 |
| Other | |||
| Lactate | -0.0765 | 0.6527 | 37 |