Table 4.
In the Beth Israel Deaconess Medical Center/St. Vincent’s cohort (100 patients), the 24-h increase in circulating heparan sulfate (an index of ongoing glycocalyx degradation) is independently associated with the volume of fluid resuscitation received over those 24 h
| Change in plasma heparan sulfate (from time of study entry to 24 hours after enrollment) | |||
|---|---|---|---|
| Variable | Parameter estimate | Standard error | p |
| Intercept | -340.19 | 276.91 | 0.22 |
| SOFA | -13.44 | 23.15 | 0.56 |
| Age | 6.50 | 4.26 | 0.13 |
| Cumulative intravenous fluids, 0-24h | 0.08 | 0.03 | 0.02 |