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. 2019 Jul 10;2019:1050285. doi: 10.1155/2019/1050285

Figure 3.

Figure 3

The target gene IL-10 of IRF4 was associated with the inhibition function of Treg cells in ITP patients. (a) IRF4 binding used by different primers of IL-10 promoter of CD4+CD25hiFoxp3+Treg cells, and CD4+CD25−Teff cells in ITP and NC groups. (b) The specific location of IRF4 binding to 5 different IL-10 primers. (c) The intensity of IRF4 binding to IL-10 DNA on Tregs in ITP and NC groups. (d) The intensity of IRF4 binding to IL-10 DNA on Teffs in ITP and NC groups. (e) The intensity of IRF4 binding to IL-10 DNA on Tregs and Teffs in ITP and NC groups. NC: normal control, ITP: ITP group. ∗p < 0. 05; ∗∗p < 0. 01.