Table 2.
HBV DNA levels of the pregnant women during pregnancy and postpartum.
| Group A (n=264) | Group B (n=136) | Group C (n=251) |
P Group B vs. C |
|
|---|---|---|---|---|
| baseline | ||||
| HBV DNA (log10 copies/mL) | 3.51±0.58 | 7.89±0.80 | 7.73±0.65 | 0.034 |
| before delivery | ||||
| HBV DNA (log10 copies/mL) | 3.89±0.45 | 7.75±0.80 | 3.60±0.36 | <0.001 |
| HBV DNA decline ≥2log10 copies/mL from baseline (n, %) | 0 | 0 | 237 (94.4%) | <0.001 |
| Undetectable HBV DNA | 60 (22.7%) | 0 | 21 (8.4%) | |
| 7 months postpartum | ||||
| HBV DNA (log10 copies/mL) | 3.85±0.47 | 7.74±0.89 | 3.25±0.21 | <0.001 |
| HBV DNA decline ≥2 log10 copies/mL from baseline (n, %) | 0 | 0 | 251 (100%) | <0.001 |
| Undetectable HBV DNA | 63 (23.9%) | 0 | 132 (52.6%) | <0.001 |
| 1 year postpartum | ||||
| HBV DNA (log10 copies/mL) | 3.83±0.47 | 7.71±0.80 | 3.21±0.20 | <0.001 |
| HBV DNA decline ≥ 2 log10 copies/mL from baseline (n, %) | 0 | 0 | 251 (100%) | <0.001 |
| Undetectable HBV DNA | 64 (24.2%) | 0 | 151 (60.2%) | <0.001 |
Values are reported as mean ± standard deviation, compared with t test; or number (percentage), compared with chi-square test, unless otherwise indicated. Undetectable HBV DNA: HBV DNA < 103 copies/mL. n, number of patients.