Table 5.
Risk factors for MTCT of HBV.
| Case/exposed, % | Univariate OR (95% CI) | Adjusted OR (95% CI) | |
|---|---|---|---|
| Age | |||
| <35 | 27/595, 4.54% | 1 | |
| ≥35 | 3/56, 5.36% | 1.19 (0.35-4.06) | |
| HBeAg status | |||
| Negative | 8/186, 4.30% | 1 | |
| Positive | 22/465, 4.73% | 1.10 (0.46-2.92) | |
| HBV DNA before delivery | |||
| <106 copies/mL | 14/264, 5.30% | 1 | |
| ≥106 copies/mL | 16/387, 4.13% | 1.39 (1.17-1.64) | 1.21 (1.02-1.44) |
| ALT at baseline (U/L) | |||
| 0-40 | 10/218, 4.59% | 1 | |
| 41-80 | 9/178, 5.06% | 1.11 (0.44-2.79) | |
| >80 | 11/255, 4.31% | 0.94 (0.39-2.25) | |
| Telbivudine treatment | |||
| No | 29/400, 7.25% | 1 | |
| Yes | 1/251, 0.40% | 0.05 (0.01-0.38) | 0.07 (0.01-0.55) |
| Gestation week | |||
| ≥37 weeks | 29/620, 4.68% | 1 | |
| <37 weeks | 1/31, 3.23% | 0.68 (0.09-5.16) | |
| Mode of delivery | |||
| Vaginal delivery | 22/148, 14.86% | 1 | |
| Caesarean section | 8/503, 1.59% | 0.09 (0.03-0.22) | 0.72 (0.31-1.69) |
| Fetal distress | |||
| No | 27/515, 5.24% | 1 | |
| Yes | 3/136, 2.21% | 0.41 (0.12-1.36) | |
| Postpartum hemorrhage | |||
| No | 28/614, 4.56% | 1 | |
| Yes | 2/37, 5.41% | 1.20 (0.27-5.22) | |
| Meconium staining of the amniotic fluid | |||
| No | 27/521, 5.18% | 1 | |
| Yes | 3/130, 2.31% | 0.43 (0.13-1.45) | |
| Premature rupture of membrane | |||
| No | 28/585, 4.79% | 1 | |
| Yes | 2/66, 3.03% | 0.62 (0.14-2.67) |