Table 4. Unadjusted and multivariable-adjusted odds ratios for PPsV23 vaccination in adults, according to distinct study covariables, Catalonia, Spain, 2017 (n = 2,057,656).

Characteristic	Unadjusted			Multivariable-adjusted
	OR	95% CI	p	OR	95% CI	p
Age
50–64 years (reference)	1.00	Reference	< 0.001	1.00	Reference	< 0.001
65–79 years	16.91	16.77–17.05		14.21	14.09–14.34
≥ 80 years	42.68	42.22–43.16		30.63	30.27–31.00
Sex
Male (reference)	1.00	Reference	< 0.001	1.00	Reference	< 0.001
Female	1.11	1.10–1.12		1.05	1.04–1.05
Chronic bronchitis/emphysema	4.71	4.66–4.76	< 0.001	3.64	3.58–3.71	< 0.001
Asthma	2.02	1.99–2.05	< 0.001	2.21	2.17–2.25	< 0.001
Congestive heart failure	7.45	7.30–7.60	< 0.001	1.51	1.48–1.55	< 0.001
Coronary artery disease	3.87	3.82–3.92	< 0.001	1.61	1.59–1.64	< 0.001
Diabetes mellitus	4.64	4.61–4.68	< 0.001	3.74	3.70–3.78	< 0.001
Cirrhosis	6.21	6.13–6.29	< 0.001	1.81	1.70–1.92	< 0.001
Chronic renal disease	2.15	2.05–2.25	< 0.001	1.61	1.58–1.63	< 0.001
Cancer	2.56	2.54–2.59	< 0.001	1.32	1.31–1.34	< 0.001
Alcoholism	0.87	0.85–0.88	< 0.001	1.15	1.12–1.18	< 0.001
Smoking	0.34	0.33–0.34	< 0.001	0.68	0.67–0.69	< 0.001

CI: confidence interval; OR: odds ratio; PPsV23: 23-valent pneumococcal polysaccharide vaccine.