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. 2019 Mar 7;17(1):1–10. doi: 10.18502/ijrm.v17i1.3815

Table 2.

Changes in the angiogenic factors (sFlt-1 and PlGF) between the preterm (< 37 weeks) or term ( 37 weeks) of preeclampsia.


Angiogenic factors MD (95% CI) Heterogeneity
I2 p-value
sFlt-1 < 37 Wk of gestation 1.71 (0.63, 2.72) 98.3 < 0001
37 Wk of gestation 0.44 (–0.60, 1.48) 97.7 < 0001
PlGF < 37 Wk of gestation –1.01 (–1.46, –0.56) 91.6 < 0001
37 Wk of gestation –0.85 (–1.73,0.03) 96.8 < 0001
Note: MD: The mean difference;
sFlt-1: Soluble fms-like tyrosine kinase 1; PlGF: Placental growth factor.