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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1796–1805. doi: 10.1161/ATVBAHA.117.310672

Figure 1. Vector expression and efficiency in vivo.

Figure 1

Bioluminescence imaging (BLI) was performed at days 1, 3, 9, and 15 after intravenous injection of MC-Luc. Subsequently, BLI was performed with the Xenogen In Vivo Imaging System with administration of D-Luciferin at a dose of 375 mg/kg of body weight.

A) Localization and intensity of bioluminescence.

B) Quantification of bioluminescence per organ

C) IL-10 plasma levels of mice at d7 after transfection with MC IL-10; n=5 per group, ** = p≤0.01.

D) Gene expression analysis (q-rtPCR) of IL-10 after 28days of AngII treatment in homogenized tissue

E) Gene expression of splenic tissue for IL-10, foxp3 and TNF at d28 after AngII infusion.

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