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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1796–1805. doi: 10.1161/ATVBAHA.117.310672

Figure 5. T lymphocyte differentiation in human PBMCs after AngII priming and stimulation.

Figure 5

Human PBMCs were isolated and primed with AngII or AngII/IL-10 for 24 hours before cells were activated with LPS (24h) to further evaluate gene expression of T cell characterizing markers; n=9/18/19

A) Relative expression of FOXP3 over GAPDH in unprimed, AngII-primed, and AngII/IL-10 primed PBMCs; ## = p≤0.01 vs. untreated; p=.0.07 in AngII IL-10 vs. AngII.

B) Relative expression of GranzymeB (GZMB) in unprimed, AngII, AngII/IL-10 PBMCs; * = p≤0.05 vs. AngII.

C) Ratio (relative expression) of FOXP3 over GRZB; * = p≤0.05 vs. AngII.

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