Table 1.
All patients (n = 542) | |
---|---|
Sex – female | 300 (55.4) |
Age (year)a | 53 (43–62) |
Symptomatic | 272 (50.2) |
Incidental | 258 (47.6) |
Non-functional tumor | 435 (80.3) |
Functional tumor | 107 (19.7) |
Insulinoma | 103 (18.9) |
Glucagonoma | 1 (0.2) |
Somatostatinoma | 1 (0.2) |
VIPoma | 2 (0.4) |
Tumor location | |
Head/neck/uncinate | 256 (47.2) |
Body/tail | 286 (52.8) |
Multiple | 23 (4.2) |
Tumor size (mm)b | 22.0 (14.0–37.3) |
Synchronous liver metastasis | 19 (3.5) |
Surgical approach | |
Open | 273 (50.4) |
Minimally invasive | 269 (49.6) |
Type of resection | |
PPPD or PD | 199 (36.7) |
Distal pancreatectomy | 249 (45.9) |
Central pancreatectomy | 32 (5.9) |
Enucleation | 50 (9.2) |
Total pancreatectomy | 12 (2.2) |
Combined operation | |
Hepatectomy and/or intraoperative RFA | 19 (3.5) |
Portal vein resection | 16 (3.0) |
Others | 1 (0.2) |
Morbidity (Dindo and Clavien’s classification) | |
Overall | 122 (22.5) |
Grade I/II | 94 (17.3) |
Grade III/IV | 27 (5.0) |
Pancreatic fistula | |
Grade A | 102 (18.8) |
Grade B | 34 (6.3) |
Grade C | 4 (0.7) |
Postoperative mortality | 1 (0.2) |
Adjuvant treatment | 27 (5.0) |
Grade | |
G1 | 250 (46.1) |
G2 | 154 (28.4) |
G3 | 34 (6.3) |
Unknown | 104 (19.2) |
AJCC tumor category | |
T1/T2 | 429 (79.2) |
T3/T4 | 113 (20.8) |
N1 status | 67 (12.4) |
M1 status | 20 (3.7) |
Lymphovascular invasion | 122 (22.5) |
Perineueral invasion | 82 (15.1) |
Resection margin | 31 (5.7) |
Values in parentheses are percentages.
aValues are median (i.q.r.). bValues are median (i.q.r.).
AJCC, American Joint Committee on Cancer; G, tumor grade (World Health Organization classification, 2010); PD, pancreaticoduodenectomy; PPPD, pylorus-preserving pancreaticoduodenectomy; RFA, radiofrequency ablation.