. 2019 Jul 2;8(8):1089–1096. doi: 10.1530/EC-19-0303
This work is licensed under a Table 3.
NOTCH1 positivity according to histotype.
| Positivity (TOT) | Pos (%) | Neg (%) |
|---|---|---|
| NH (2) | 0 (0) | 2 (100) |
| FA (5) | 3 (60) | 2 (40) |
| HA (5) | 0 (0) | 5 (100) |
| HTT (6) | 0 (0) | 6 (100) |
| PTC (48) | 45 (93.75) | 3 (6.25) |
| FTC (12) | 5 (41.6) | 7 (58.3) |
| HCC (5) | 1 (20) | 4 (80) |
| MTC (9) | 2 (22.2) | 7 (77.8) |
| PDTC (6) | 4 (66.7) | 2 (33.3) |
| ATC (8) | 3 (37.5) | 5 (62.5) |
| Pattern (TOT-NOTCH1+) | Cytoplasmic (%) | Luminal (%) |
| FA (3) | 3 (100) | 0 (0) |
| PTC (45) | 0 (0) | 45 (100) |
| FTC (5) | 3 (60) | 2 (40) |
| HCC (1) | 1 (100) | 0 (0) |
| MTC (2) | 2 (100) | 0 (0) |
| PDTC (4) | 3 (75) | 1 (25) |
| ATC (3) | 3* (100) | 0 (0) |
*One case of ATC shows both cytoplasmic and luminal positivity.
ATC, anaplastic thyroid carcinoma; FA, follicular adenoma; FTC, follicular thyroid carcinoma; HA, Hürthle cell adenoma; HCC, Hürthle cell carcinoma; HTT, hyalinizing trabecular tumor; MTC, medullary thyroid carcinoma; NH, nodular hyperplasia; PDTC, poorly differentiated thyroid carcinoma; PTC, papillary thyroid carcinoma.