Table 1.
Men (n = 1926) | Women (n = 2025) | P | |
---|---|---|---|
Age (years) | 53 (41–65) | 52 (40–64) | <0.01 |
Smoking (%) | <0.01 | ||
Never smokers | 24.87 | 46.76 | |
Former smokers | 45.79 | 29.14 | |
Current smokers | 29.34 | 24.10 | |
Fasting (≥8 h) (%) | 58.62 | 64.64 | <0.01 |
Alcohol consumption (g/day) | 7.9 (2.1–18.5) | 1.8 (0.4–4.9) | <0.01 |
Waist circumference (cm) | 97 (89–106) | 84 (75–94) | <0.01 |
Body mass index (kg/m2) | 28 (26–31) | 27 (24–31) | <0.01 |
hsCRP (mg/L) | 1.2 (0.6–2.5) | 1.5 (0.8–3.4) | <0.01 |
HbA1c (%) | 5.3 (5.0–5.8) | 5.2 (4.8–5.6) | <0.01 |
Glucose (mmol/L) | 5.6 (5.2–6.2) | 5.2 (4.9–5.7) | <0.01 |
Total triglycerides (mmol/L) | 1.6 (1.1–2.3) | 1.3 (0.9–1.8) | <0.01 |
Systolic blood pressure (mmHg) | 133 (124–144) | 120 (110–133) | <0.01 |
Diastolic blood pressure (mmHg) | 80 (73–86) | 74 (69–81) | <0.01 |
ALT (μkatal/L) | 0.46 (0.34–0.64) | 0.31 (0.24–0.41) | <0.01 |
AST (μkatal/L) | 0.33 (0.26–0.41) | 0.26 (0.21–0.33) | <0.01 |
AP (μkatal/L) | 1.10 (0.96–1.30) | 1.10 (0.89–1.40) | <0.01 |
GGT (μkatal/L) | 0.64 (0.47–0.94) | 0.43 (0.35–0.56) | <0.01 |
Hepatic steatosis (US+) (%) | 47.09 | 34.12 | <0.01 |
Liver fat contenta (MRI) (%) | 4.95 (2.84–9.26) | 3.25 (2.15–6.93) | <0.01 |
Hepatic steatosis (LFCa >5%) (%) | 49.29 | 34.86 | <0.01 |
Adiponectin (μg/mL) | 5.4 (3.7–7.6) | 8.9 (6.2–12.2) | <0.01 |
Chemerin (ng/mL) | 95.4 (80.5–113.9) | 102.4 (85.7–122.0) | <0.01 |
Continuous data are expressed as median (1st–3rd quartile); nominal data are given as percentages. Chi-square test (nominal data) or Mann–Whitney U test (continuous data) was used for comparisons between men and women.
aMagnetic resonance imaging (MRI) examinations were performed in a subsample of 1735 subjects.
ALT, alanine aminotransferase; AP, alkaline phosphatase; AST, aspartate aminotransferase; GGT, gamma-glutamyl-transferase; HbA1c, glycated hemoglobin; hsCRP, high-sensitivity C-reactive protein; LFC, liver fat content; US+, presence of an hyperechogenic liver defined via ultrasonography (US).