Table 3.

Results from sex-specific logistic regression analyses: associations of circulating chemerin and adiponectin with the odds of hepatic steatosis as defined by two different criteria.

		Cases	Chemerin per 29 ng/mL		Adiponectin per 5 μg/mL
			OR (95% CI)	P	OR (95% CI)	P
Hepatic steatosis defined based on ultrasound (US)
Men	US−	1019	Ref.		Ref.
	US+	907	1.16 (1.02–1.31)	0.02	0.56 (0.47–0.66)	<0.01
Fasting men	US−	602	Ref.		Ref.
	US+	527	1.24 (1.05–1.46)	0.01	0.60 (0.48–0.74)	<0.01
Women	US−	1334	Ref.		Ref.
	US+	691	0.97 (0.86–1.10)	0.65	0.79 (0.70–0.89)	<0.01
Fasting women	US−	871	Ref.		Ref.
	US+	438	1.04 (0.88–1.23)	0.65	0.86 (0.74–0.99)	0.05
Hepatic steatosis defined based on liver fat content (LFC–MRI)
Men	LFCa ≤5%	426	Ref.		Ref.
	LFCa >5%	414	1.42 (1.14–1.76)	<0.01	0.52 (0.40–0.69)	<0.01
Fasting men	LFCa ≤5%	295	Ref.		Ref.
	LFCa >5%	282	1.34 (1.02–1.75)	0.03	0.53 (0.38–0.75)	<0.01
Women	LFCa ≤5%	583	Ref.		Ref.
	LFCa >5%	312	1.36 (1.09–1.71)	<0.01	0.58 (0.47–0.72)	<0.01
Fasting women	LFCa ≤5%	459	Ref.		Ref.
	LFCa >5%	227	1.37 (1.05–1.80)	0.02	0.65 (0.51–0.84)	<0.01

Presented are the odds ratios (OR), together with the 95% confidence interval (95% CI) and the P value. Logistic regression models were adjusted for age, waist circumference, glycated hemoglobin, systolic blood pressure, total triglycerides and high-sensitivity C-reactive protein.

^aMagnetic resonance imaging (MRI) examinations were performed in a subsample of 840 men (577 of them fasting) and 895 women (686 of them fasting).

LFC, liver fat content; ref, reference group; US⁺, presence of a hyperechogenic liver defined via ultrasonography (US); US⁻, no presence of a hyperechogenic liver.