Differences in change in grip strength for age groups, BMI groups, routes of hormonal administration, estradiol concentrations and testosterone concentrations. Data are presented as means with 95% CIs. Reference values (25th and 75th percentile) are based on the mean age of this population. For transwomen the 25th percentile is 25 kg and the 75th percentile is 31 kg. For transmen the 25th percentile is 36 kg and the 75th percentile is 50 kg (18). (A) Grip strength change over 12 months between age, adjusted for administration route. (B) Grip strength change over 12 months between BMI groups. (C) Grip strength change over 12 months between different administration routes, adjusted for age. (D) Grip strength change over 12 months between different hormone concentrations.