Table 2.
Odd ratios with 95% CIs for the onset of vascular stenosis due to elevated SUA
| Hyperuricaemia (n = 270) | Non‐hyperuricaemia (n = 2374) | SUA risk | Odd ratios (95% CIs) | |||
|---|---|---|---|---|---|---|
| Unadjusted | P value | Adjusted | P value | |||
| Vascular stenosis | ||||||
| 146 (54.1) | 824 (34.7) | Hyperuricaemia | 2.22 (1.72‐2.86) | <0.001 | 1.75 (1.32‐2.31) | <0.001 |
| per SUA1 mg/dL | 1.39 (1.31‐1.47) | <0.001 | 1.29 (1.21‐1.38) | <0.001 | ||
| ICAS | ||||||
| 32 (11.9) | 226 (9.5) | Hyperuricaemia | 1.28 (0.86‐1.90) | 0.222 | 1.38 (0.91‐2.10) | 0.129 |
| per SUA1 mg/dL | 1.10 (1.01‐1.19) | 0.026 | 1.23 (1.11‐1.36) | <0.001 | ||
| ECAS | ||||||
| 126 (46.7) | 564 (23.8) | Hyperuricaemia | 2.81 (2.17‐3.63) | <0.001 | 2.17 (1.61‐2.94) | <0.001 |
| per SUA1 mg/dL | 1.61 (1.51‐1.71) | <0.001 | 1.47 (1.36‐1.59) | <0.001 | ||
Model 1: unadjusted. Model 2: fully adjusted for age, sex, educational level, income, smoking, alcohol consumption, hypertension, hyperlipidaemia, diabetes mellitus, body mass index (BMI), C‐reactive protein (CRP), serum albumin (ALB) and estimated glomerular filtration rate (eGFR). Vascular stenosis was defined as the presence of ICAS or ECAS at ≥1 site. Abbreviations: ECAS, extracranial artery stenosis; ICAS, intracranial artery stenosis.