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. 2011 Nov 28;35(2):101–106. doi: 10.1002/clc.20995

Table 1.

Characteristics of the Study Population According to the Pure Form and Mixed Form of Apical Hypertrophic Cardiomyopathy at Baseline

Features All Patients (n = 208) Pure Form (n = 134) Mixed Form (n = 74) P Value
Male, no. (%) 153 (73.6) 97 (72.4) 56 (75.7) NS
Age at diagnosis, y 52.2 ± 12.4 53.7 ± 11.6 49.6 ± 13.4 0.020a
Family history of HCM, no. (%) 29 (13.9) 11 (8.2%) 18 (24.3%) 0.013a
Hypertension, no. (%) 82 (39.4) 58 (43.3) 24 (32.4) NS
Heart rate, times/min 69.9 ± 9.7 70.0 ± 9.6 69.8 ± 10.0 NS
NYHA class ≥III, no. (%) 15 (7.2) 4 (3.0) 11 (14.9) 0.003a
ECG, no. (%)
 T‐wave inversion 190 (91.3) 131 (97.8) 59 (79.7) NS
 GNT 60 (28.8) 42 (32.1) 18 (24.3) NS
 LVHV 125 (60.1) 84 (62.7) 41 (55.4) NS
 Q waves 16 (7.7) 9 (6.7) 7 (9.5) NS
Echocardiography
 LVATmax, mm 40 40 37
 LVAT, mm 19.9 ± 4.3 19.2 ± 4.1 21.3 ± 4.3 <0.001a
 IVST, mm 14.0 ± 6.4 11.6 ± 4.6 18.4 ± 7.1 <0.001a
 LVPWT, mm 9.9 ± 1.5 9.7 ± 1.5 10.3 ± 1.4 0.001a
 Ratio LVAT/LVPWT 2.1 ± 0.8 2.03 ± 0.53 2.21 ± 1.16 NS
 LAd, mm 37.3 ± 6.0 36.5 ± 5.3 38.7 ± 6.7 0.010a
 LVEDd, mm 47.8 ± 5.2 48.7 ± 5.1 46.3 ± 5.1 0.001a
 LVESd, mm 30.0 ± 4.7 30.4 ± 4.7 29.3 ± 4.7 NS
 LVEF, % 66.4 ± 9.3 66.6 ± 9.6 66.01 ± 8.9 NS
VE, m/s 0.72 ± 0.19 0.71 ± 0.19 0.72 ± 0.19 NS
VA, m/s 0.84 ± 0.23 0.82 ± 0.24 0.88 ± 0.20 NS
Ratio, VE/VA 0.91 ± 0.37 0.93 ± 0.37 0.87 ± 0.36 NS

Abbreviations: ECG, electrocardiogram; GNT, giant negative T waves; HCM, hypertrophic cardiomyopathy; IVST, interventricular septum thickness; LAd, left atrial end‐systolic diameter; LVAT, left ventricular apical thickness; LVEDd, left ventricular end‐diastolic diameter; LVEF, left ventricular ejection fraction; LVESd, left ventricular end‐systolic diameter; LVHV, left ventricular high voltage; LVPWT, left ventricular posterior wall thickness; NS, denotes not significant, comparing pure form with mixed form; NYHA, New York Heart Association; VA, peak end‐diastolic mitral flow velocity; VE, peak early‐diastolic mitral flow velocity.

Data are presented as number (%) or mean ± standard deviation.

a

P < 0.05.