Table 2.
ASD | VSD | PDA | |||||||
---|---|---|---|---|---|---|---|---|---|
Baseline | 12 Weeks | P | Baseline | 12 Weeks | P | Baseline | 12 Weeks | P | |
6MWD, m | 377.2 ± 68.7 | 436.0 ± 70.4 | <0.001 | 371.2 ± 66.0 | 413.7 ± 83.1 | 0.006 | 384.3 ± 90.2 | 440.9 ± 71.8 | 0.006 |
Borg dyspnea index | 2.6 ± 1.3 | 1.8 ± 1.0 | 0.041 | 2.6 ± 1.5 | 2.4 ± 1.5 | 0.496 | 2.2 ± 1.4 | 1.9 ± 1.5 | 0.647 |
WHO functional class | 2.3 ± 0.5 | 2.1 ± 0.6 | 0.189 | 2.3 ± 0.4 | 1.8 ± 0.6 | 0.002 | 2.3 ± 0.6 | 1.8 ± 0.5 | 0.029 |
SaO2, %a | 90.98 ± 5.04 | 93.26 ± 2.95 | 0.019 | 88.93 ± 4.83 | 89.31 ± 5.09 | 0.748 | 86.49 ± 3.88b | 87.31 ± 4.60 | 0.598 |
MAP, mm Hg | 87.82 ± 10.74 | 86.60 ± 7.31 | 0.631 | 84.54 ± 7.14 | 85.03 ± 10.03 | 0.809 | 86.48 ± 10.47 | 82.42 ± 11.79 | 0.082 |
Abbreviations: 6MWD, 6‐minute walk distance; ASD, atrial septal defects; MAP, mean systemic arterial pressure; PDA, patent ductus arteriosus; VSD, ventricular septal defects; SaO2, arterial oxygen saturation; WHO, World Health Organization.
ASD group, n = 13; VSD group, n = 16; and PDA group, n = 11.
Significant compared with ASD group at baseline, P = 0.024.