Table 1.

Summary of Anticoagulation Reversal Agents

	Reversal Agents	Monitoring	Comments
Warfarin	Vitamin K, FFP, rFVIIa, PCC, aPCC	PT/INR	Vitamin K has a delayed reversal effect. To significantly increase coagulation proteins, 2 to 10 L of FFP may be required. PCCs and rFVIIa are powerful procoagulant agents that can significantly increase the risk of thrombotic events.
Rivaroxaban	rFVIIa, PCC, aPCC	PT, TT, anti‐factor Xa
Dabigatran	rFVIIa	ECT, aPTT, TT

Abbreviations: aPCC, activated prothrombin complex concentrate; aPTT, activated partial thromboplastin time; ECT, ecarin clotting time; FFP, fresh frozen plasma; INR, international normalized ratio; PCC, prothrombin complex concentrate; PT, prothrombin time; rFVIIa, recombinant factor VIIIa; TT, thrombin time.