Table 2.
No. of Patients | No. with AF | Days at Risk | Incidence/1000 y | RR | 95% CI | RR1 a | 95% CI | RR2 b | 95% CI | |
---|---|---|---|---|---|---|---|---|---|---|
C (CHF) | ||||||||||
No | 52972 | 2432 | 43891162 | 20.22 | 1.00 | 1.00 | 1.00 | |||
Yes | 4664 | 337 | 2651748 | 46.39 | 2.22 | 1.98–2.48 | 1.89 | 1.68–2.12 | 1.83 | 1.63–2.06 |
H (HT) | ||||||||||
No | 26608 | 1054 | 21753369 | 17.71 | 1.00 | 1.00 | 1.00 | |||
Yes | 31028 | 1715 | 24789541 | 25.29 | 1.42 | 1.32–1.53 | 1.38 | 1.28–1.49 | 1.36 | 1.26–1.47 |
A75 (age ≥75 y) | ||||||||||
No | 26539 | 910 | 24675067 | 13.48 | 1.00 | 1.00 | 1.00 | |||
Yes | 31097 | 1859 | 21867843 | 31.07 | 2.26 | 2.08–2.44 | 2.13 | 1.97–2.31 | 2.39 | 2.06–2.77 |
3.52 | 3.07–4.04 | |||||||||
4.34 | 3.72–5.06 | |||||||||
D (DM) | ||||||||||
No | 45501 | 2230 | 37116918 | 21.96 | 1.00 | 1.00 | 1.00 | |||
Yes | 12135 | 539 | 9425992 | 20.90 | 0.95 | 0.86–1.04 | 0.88 | 0.80–0.97 | 0.88 | 0.80–0.97 |
S (stroke) | ||||||||||
No | 43272 | 2056 | 35540442 | 21.14 | 1.00 | 1.00 | 1.00 | |||
Yes | 14346 | 713 | 11002468 | 23.69 | 1.11 | 1.02–1.21 | 0.99 | 0.91–1.08 | 0.96 | 0.88–1.05 |
Sex | ||||||||||
F | 27761 | 1443 | 21877385 | 24.11 | 1.00 | 1.00 | 1.00 | |||
M | 29875 | 1326 | 24665525 | 19.65 | 0.82 | 0.76–0.88 | 0.94 | 0.87–1.02 | 0.97 | 0.90–1.05 |
CHADS2 score | ||||||||||
0 | 9048 | 226 | 8571052 | 9.64 | 1.00 | |||||
1 | 17258 | 774 | 14504221 | 19.50 | 2.00 | 1.73–2.33 | ||||
2 | 14335 | 810 | 11244789 | 26.33 | 2.69 | 2.32–3.11 | ||||
3 | 8853 | 499 | 6657935 | 27.39 | 2.79 | 2.38–3.26 | ||||
4 | 5847 | 332 | 4197717 | 28.91 | 2.93 | 2.47–3.47 | ||||
5 | 1993 | 111 | 1221588 | 33.21 | 3,32 | 2.64–4.16 | ||||
6 | 302 | 17 | 145608 | 42.67 | 4.16 | 2.54–6.80 |
Abbreviations: AF, atrial fibrillation; CHF, congestive heart failure; CI, confidence interval; DM, diabetes mellitus; F, female; HT, hypertension; M, male; RR, relative risk.
RR1: C, H, A75, D, S, and sex included in the model.
RR2: C, H, age 4 categories, D, S, and sex included in the model.