Table 2.
Risk Factors for Operative Mortality in the Whole Cohort and in Patients With or Without Postoperative Atrial Fibrillation (N = 6728)
| Univariate Analysis | Multivariate Analysis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| All Patients | All Patients | Patients With POAF | Patients Without POAF | |||||||||
| Univariate OR | CI | P Value | OR in the Whole Cohort | CI | P Value | OR in Patients With POAF | CI | P Value | OR in Patients Without POAF | CI | P Value | |
| Age, y | 1.08 | 1.06–1.11 | <0.001 | 1.07 | 1.04–1.10 | <0.001 | 1.06 | 1.01–1.10 | 0.01 | 1.07 | 1.04–1.11 | <0.001 |
| Female gender | 1.99 | 1.29–3.08 | 0.002 | — | — | — | — | — | — | — | — | — |
| History of stroke | 2.41 | 1.20–4.85 | 0.01 | — | — | — | 2.67 | 1.09–6.51 | 0.03 | — | — | — |
| Previous myocardial infarction | 1.49 | 0.97–2.27 | 0.07 | — | — | — | — | — | — | — | — | — |
| Diabetes mellitus | 1.58 | 1.03–2.42 | 0.03 | — | — | — | — | — | — | — | — | — |
| Hypertension | 2.59 | 1.49–4.52 | 0.001 | 2.10 | 1.19–3.84 | 0.01 | 2.10 | 0.90–4.90 | 0.09 | 2.42 | 1.07–5.52 | 0.04 |
| BMI, kg/m2 | ||||||||||||
| <20 | 2.61 | 1.06–6.46 | 0.04 | — | — | — | — | — | — | — | — | — |
| 20 to 25 | Reference | N/A | N/A | — | — | — | — | — | — | — | — | — |
| 25 to 30 | 0.77 | 0.46–1.29 | 0.32 | — | — | — | — | — | — | — | — | — |
| >30 | 0.86 | 0.49–1.50 | 0.59 | — | — | — | — | — | — | — | — | — |
| COPD | 2.51 | 1.52–4.16 | <0.001 | 1.82 | 1.07–3.11 | 0.03 | — | — | — | 2.14 | 1.03–4.44 | 0.04 |
| Renal failure | 3.52 | 1.97–6.30 | <0.001 | 2.17 | 1.16–4.05 | 0.02 | 2.46 | 1.07–5.65 | 0.04 | — | — | — |
| LV ejection fraction <50% | 2.48 | 1.60–3.85 | <0.001 | 1.95 | 1.28–3.17 | 0.004 | 1.98 | 1.03–3.80 | 0.04 | 2.25 | 1.20–4.24 | 0.01 |
| Emergent surgery | 2.15 | 1.41–3.29 | <0.001 | 1.92 | 1.23–3.00 | 0.004 | — | — | — | 2.16 | 1.16–4.03 | 0.02 |
| CPB time >120 minutes | 4.21 | 2.21–8.04 | <0.001 | 4.13 | 2.04–8.34 | <0.001 | 5.73 | 2.28–14.40 | <0.001 | — | — | — |
| Preoperative medication | ||||||||||||
| Statins | 0.59 | 0.37–0.94 | 0.02 | — | — | — | 0.38 | 0.20–0.72 | 0.003 | — | — | — |
| ACEI | 1.29 | 0.85–1.97 | 0.23 | — | — | — | — | — | — | — | — | — |
| Aspirin | 0.87 | 0.53–1.42 | 0.58 | — | — | — | — | — | — | — | — | — |
| β‐Blockers | 0.96 | 0.58–1.60 | 0.87 | — | — | — | — | — | — | — | — | — |
| Perioperative complications | ||||||||||||
| POAF | 2.47 | 1.62–3.75 | <0.001 | 1.78 | 1.14–2.81 | 0.01 | N/A | N/A | N/A | N/A | N/A | N/A |
| Myocardial infarction | 1.58 | 0.84–2.99 | 0.16 | — | — | — | 3.44 | 1.56–7.61 | 0.002 | — | — | — |
Abbreviations: ACEI, angiotensin conversion enzyme inhibitors; BMI, body mass index; CI, confidence interval; COPD, chronic obstructive pulmonary disease; CPB, cardiopulmonary bypass; LV, left ventricular; N/A, not applicable; OR, odds ratio; POAF, postoperative atrial fibrillation. Only the variables with a P value <0.2 are shown.