Table 3.
Biomarker | Cumulative Incidence (95% CI) | Hazard Ratio (95% CI) | |
---|---|---|---|
MACE, Adjusted for Age and Sex | MACE, Multivariate Adjusted | ||
Lipoprotein (a) | |||
Tertile 1 | 10% (2‐18) | 1.00 (reference) | 1.00 (reference) |
Tertile 2 | 31% (19‐44) | 3.7 (1.4‐10.1) | 3.3 (1.2‐9.2) |
Tertile 3 | 31% (18‐43) | 3.5 (1.3‐9.6) | 3.1 (1.1‐8.6) |
P for trend | 0.04 | 0.06 | |
Interleukin‐10 | |||
Tertile 1 | 17% (7‐28) | 1.00 (reference) | 1.00 (reference) |
Tertile 2 | 24% (13‐35) | 1.5 (0.63‐3.5) | 1.3 (0.52‐3.3) |
Tertile 3 | 29% (17‐41) | 2.1 (0.92‐5.0) | 2.1 (0.92‐5.0) |
Detectable vs nondetectable | 1.6 (0.76‐3.4) | 1.5 (0.69‐3.3) | |
C‐reactive protein | |||
Tertile 1 | 21% (10‐32) | 1.00 (reference) | 1.00 (reference) |
Tertile 2 | 20% (10‐31) | 0.93 (0.40‐2.2) | 0.87 (0.37‐2.1) |
Tertile 3 | 32% (20‐45) | 1.6 (0.72‐3.3) | 1.7 (0.77‐3.8) |
P for trend | 0.20 | 0.17 |
Abbreviations: CI, confidence interval; MACE, major adverse cardiac events (death, nonfatal myocardial infarction, and repeat revascularization).
Multivariate adjusted: adjusted for age, sex, smoking, diabetes mellitus, hypertension, and hypercholesterolemia.