Table 2.

Changes in Laboratory Parameters After Drug Treatment (N = 60)

Parameter		Atorvastatin (N = 30)	Atorvastatin/ Ezetimibe (N = 30)	P Valuea
TC, mg/dL	Before	239 ± 16	43 ± 27	0.49
	After	158 ± 30	158 ± 3	0.99
	P valueb	<0.001	<0.001
TG, mg/dL	Before	128 ± 38	134 ± 52	0.63
	After	116 ± 51	117 ± 42	0.90
	P valueb	0.20	0.12
HDL‐C, mg/dL	Before	50.5 ± 8.8	49.7 ± 7.8	0.71
	After	49.7 ± 7.8	53.6 ± 12.0	0.14
	P valueb	0.46	0.02
LDL‐C, mg/dL	Before	164 ± 12	163 ± 23	0.94
	After	87 ± 23	82 ± 14	0.38
	P valueb	<0.001	<0.001
Lp‐PLA2, ng/mLc	Before	338 (101, 798)	265 (97, 1012)	0.13
	After	226 (31, 451)	250 (93, 553)	0.79
	P valueb	<0.001	0.02
IL‐6, pg/mLc	Before	1.40 (0.43, 5.38)	1.14 (0.43, 4.36)	0.15
	After	1.26 (0.42, 2.24)	1.04 (0.41, 4.03)	0.64
	P valueb	0.047	0.98
MCP‐1, pg/mL	Before	214 ± 66	227 ± 101	0.58
	After	235 ± 72	271 ± 126	0.17
	P valueb	0.33	0.14
Fibrinogen, mg/dL	Before	183 ± 31	193 ± 28	0.21
	After	175 ± 27	180 ± 16	0.32
	P valueb	0.24	0.10

Abbreviations: HDL‐C, high‐density lipoprotein cholesterol, IL‐6: interleukin‐6; LDL‐C, low‐density lipoprotein cholesterol; Lp‐PLA₂, lipoprotein associated phospholipase A₂; MCP‐1, monocyte chemoattractant protein‐1; TC, total cholesterol; TG, triglycerides.

^aComparison between groups.

^bComparison in a group before and after treatment.

^cNumbers presented as medians and ranges.