Table 3.
Multivariate Analyses on Baseline Factors Associated With 4‐Year Outcomes in Latin American Patients of the REACH Registry (n = 1816)
| Predictor | HR (95% CI) | P Value |
|---|---|---|
| All‐cause mortality | ||
| CHF | 3.810 (2.622–5.537) | <0.001 |
| BMI <20 | 2.322 (1.239–4.352) | 0.009 |
| Polyvascular diseasea | 1.690 (1.083–2.635) | 0.021 |
| Hypertension at baseline | 1.843 (1.171–2.899) | 0.008 |
| Age ≥65 y | 1.468 (1.034–2.083) | 0.033 |
| Statin use at baseline | 0.495 (0.362–0.678) | <0.001 |
| BMI ≥30 | 0.578 (0.373–0.895) | 0.014 |
| Cardiovascular mortality/MI/stroke | ||
| CHF | 2.506 (1.713–3.664) | <0.001 |
| Polyvascular diseasea | 2.043 (1.389–3.007) | <0.001 |
| Age ≥65 y | 1.617 (1.183–2.210) | 0.003 |
| Statin use at baseline | 0.470 (0.354–0.624) | <0.001 |
Abbreviations: AF, atrial fibrillation; BMI, body mass index; CHF, congestive heart failure; CI, confidence interval; DM, diabetes mellitus; HR, hazard ratio; MI, myocardial infarction; WHtR, waist‐to‐height ratio.
Polyvascular disease = 2 to 3 vascular disease locations. Only statistically significant risk factors are included in the table, but the model was fully adjusted for baseline characteristics such as sex, DM, AF, past or current smoking habit, WHtR >60, and antiplatelet or anticoagulant therapy. Variables with ≥98% registration rate were included in the model.