FIG 5.

Analysis of fecal microbiome of recipient mice cohoused with S. mansoni-infected mice. (A) Experimental design of microbiome transfer from S. mansoni-infected or uninfected (control) mice to microbiome recipient uninfected mice treated with antibiotics (ABX). (B) Principal coordinate analysis (PCoA) of the microbiota from mice cohoused with uninfected [UI(UI)] mice, MF-infected [UI(MF)] mice, or MO-infected [UI(MO)] mice (6 mice per group). (C) Pie charts of the 16 common most abundant genera for the indicated groups of mice (6 mice per group). (D) Hierarchical clustering dendrogram of bacterial genus profiles for the indicated groups of mice (6 mice per group). (E) Comparison of differential abundances for Parabacteroides, Bacteroides, Helicobacter, and Lactobacillus for the indicated groups of mice. Data are presented as means ± SEM. Statistical difference between groups was determined using two-way ANOVA followed by Tukey’s multiple-comparison test. ***, P < 0.001.