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Longevity of protection. Mice (n = 10/group) were given a primary i.p. challenge of C. dubliniensis 7, 14, or 120 days prior to C. albicans/S. aureus lethal challenge. Animals receiving no primary challenge served as the positive (lethal) control. Mice were monitored for 10 days post-lethal challenge. Data are cumulative of two separate experiments. ***, P < 0.001; ****, P < 0.0001 (for values significantly different from those of the control, by log rank Mantel-Cox test).
