TABLE 1.
Patient group (mean age [yrs] ± SD) |
Patient ID |
Patient sex |
Clinical form at treatment initiationb |
Clinical formb at 48 mo after treatment |
Progression to cardiac form or cardiac form worsening?b |
Hemoculture for T. cruzi 60 days after treatment |
Hemoculture for T. cruzi 48 mo after treatment |
Age (yrs) at 48 mo after treatment |
---|---|---|---|---|---|---|---|---|
4 males/4 females (53.1 ± 6.6) | P1 | Male | Indeterminate | Indeterminate | No | Negative | Negative | 42 |
P2 | Female | Indeterminate | Indeterminate | No | Negative | Negative | 53 | |
P3 | Female | Indeterminate | Indeterminate | No | Negative | Negative | 61 | |
P4 | Male | Indeterminate | Indeterminate | No | Negative | Negative | 62 | |
P5 | Male | Indeterminate | Indeterminate | No | Negative | Negative | 56 | |
P6 | Female | Indeterminate | Indeterminate | No | Negative | Negative | 49 | |
P7 | Male | Indeterminate | Indeterminate | No | Negative | Negative | 53 | |
P8 | Female | Indeterminate | Indeterminate | No | Negative | Negative | 49 | |
5 males/4 females (55.3 ± 10.6) | P9 | Male | Cardiac | Cardiac | No | Negative | Negative | 66 |
P10 | Male | Indeterminate | Cardiac | Yes | Negative | Negative | 37 | |
P11 | Male | Cardiac | Cardiac | No | Negative | Negative | 65 | |
P12 | Female | Indeterminate | Cardiac | Yes | Negative | Negative | 44 | |
P13 | Male | Cardiac | Cardiac | Yes | Negative | Negative | 58 | |
P14 | Female | Cardiac | Cardiac | No | Negative | Negative | 65 | |
P15 | Female | Indeterminate | Cardiac | Yes | Negative | Negative | 46 | |
P16 | Male | Cardiac | Cardiac | Yes | Negative | Negative | 62 | |
P17 | Female | Cardiac | Cardiac | No | Negative | Negative | 55 |
All patients were subjected to the following treatment regimen (according to guidelines from the 2nd Brazilian Consensus on Chagas Disease, 2016): benznidazole administered at 5 mg/kg of body weight for 60 days, three doses/day; maximum daily dose, 300 mg. P value, >0.99 (by Fisher's exact test) for patient sex; P value, 0.62 (by Student’s t test) for age. ID, identifier.
Data were determined according to guidelines from the 2nd Brazilian Consensus on Chagas Disease, 2016.