Huston 1992.

Study characteristics
Methods	RCT
Participants	Preterm very low birth weight infants
Interventions	Empirical use of partially hydrolysed casein hydrolysate formula (with 40% or 60% medium‐chain triglyceride) Non‐hydrolysed preterm formula Total N = 60
Outcomes	Food tolerance Growth rates
Notes	Department of Pediatrics, Emanuel Children's Health Care Centre, Portland, OR, USA Trial date: early 1990s Reported as abstract only
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Insufficient information ‐ only abstract available
Allocation concealment (selection bias)	Unclear risk	Insufficient information ‐ only abstract available
Blinding of participants and personnel (performance bias) All outcomes	High risk	Unlikely to be blinded
Blinding of outcome assessment (detection bias) All outcomes	High risk	Unlikely to be blinded
Incomplete outcome data (attrition bias) All outcomes	Low risk	Outcomes reported for all participants
Selective reporting (reporting bias)	Unclear risk	Protocol not available
Other bias	Unclear risk	Funder: Mead Johnson Nutritional Group