Figure 6.

BAG3‐positive HPanSteC cells promote PDACs invasion via IL‐8, MCP1, TGF‐β2 and IGFBP2 release. (A, B, E and F) BxPC3 (A and B) or SW1990 cells (E and F) were incubated with conditional media from BAG3‐overexpression HPanSteC cells in the presence of BSA or the indicated monoclonal antibodies. Transwell invasion assay was performed in the above cells. (C, D, G and H) BxPC3 (C and D) or SW1990 (G and H) cells were incubated with conditional media from BAG3‐overexpression HPanSteC cells in the presence of BSA or reCXCL6. Transwell invasion assay was performed in the above cells. *P < 0.01. Error bars indicate means ± SD