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. 2019 May 31;23(8):5466–5474. doi: 10.1111/jcmm.14429

Figure 2.

Figure 2

Effect of cord blood plasma on motor, neurological and gastrointestinal function in Parkinson's disease (PD) animals. The motor and non‐motor related Parkinsonian pathologies were observed in a gut‐induced 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine (MPTP) rat model of PD. Initially, rotarod testing did not show much benefit at 7‐d post‐transplant (A), while significant improvements in motor function were observed at the 14‐d time point (B). Additionally, significant improvements non‐motor PD dysfunction were observed in both time points for colonic motility (C,D) and the end‐of‐study charcoal meal gastrointestinal transits test (F) in MPTP lesioned rats that received CBP treatment. *,&: P < 0.05, **: P < 0.01