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. 2019 Jun 26;23(8):5165–5175. doi: 10.1111/jcmm.14385

Figure 2.

Figure 2

Overexpression of miR‐629 promoted cell proliferation, cell migration and inhibited cell apoptosis of HPASMCs. A, The expression of miR‐629 in HPASMCs after being transfected with mimics NC or miR‐629 mimics was determined by qRT‐PCR. B, Cell viability and (C) cell proliferation of HPASMCs after being transfected with mimics NC or miR‐629 mimics was detected by CCK‐8 assay and BrdU assay respectively. (D and E) The expression of PCNA mRNA and protein in HPASMCs after being transfected with mimics NC or miR‐629 mimics were determined by qRT‐PCR and western blot respectively. (F) Cell migration of HPASMCs after being transfected with mimics NC or miR‐629 mimics was determined by transwell migration assay. (G and H) The caspase‐3 activity and the expression of caspase‐3 protein in HPASMCs after being transfected with mimics NC or miR‐629 mimics were determined by Caspase‐3 activity assay and western blot respectively. Data are expressed as mean ± standard deviation; n = 3. * P < 0.05, ** P < 0.01 and *** P < 0.001 versus control groups