Table 4.

The effect of micro- and nanoparticles of MnO${}_{\mathbf{2}}$ on serum concentrations of FSH, estradiol, and testosterone

Groups	FSH (µIU/L)	Estradiol (Pg/mL)	Testosterone(ng/mL)
Control	1.75 $\pm$ 0.43	46 $\pm$ 2.8	0.85 $\pm$ 0.05
vehicle	3.6 $\pm$ 1.05	40 $\pm$ 5.7	4.01 $\pm$ 2.4
Micro-MnO${}_{\mathbf{2}}$	4.9 $\pm$ 1.55	39.6 $\pm$ 6.01 22	2.91 $\pm$ 0.73
Nano-MnO${}_{\mathbf{2}}$	3.4 $\pm$ 0.4	39.4 $\pm$ 4.04	4.37 $\pm$ 0.88
Note: Values are mean $\pm$ STD; MnO${}_2$: Manganese Dioxide; FSH: Follicle-stimulating Hormone