Table 1.

Comparison of Baseline Characteristics for 2,323 Participants in the Health, Aging and Body Composition (Health-ABC) Study

	Tertiles of Inflammatory Markers
	Overall	C-reactive Protein (ug/ml)			Interleukin-6 (pg/ml)			Tumor Necrosis Factor-α (pg/ml)
		T1	T2	T3	T1	T2	T3	T1	T2	T3
Total Participants (Cases)	2323 (89, 4%)	718 (26, 4%)	715 (21, 3%)	716 (39, 5%)	734 (17, 2%)	735 (23, 3%)	734 (46, 6%)	721 (20, 3%)	720 (32, 4%)	720 (28, 4%)
Exposure, Median(SD)	5.9 (9.8)	0.7 (0.6)	3.1 (0.9)	19.9 (52.7)	1.1 (0.3)	2.0 (0.3)	5.2 (3.2)	2.1 (0.4)	3.1 (0.3)	5.0 (1.9)
Age at baseline, mean (SD)	73.5 (2.9)	73.5 (2.8)	73.6 (2.9)	73.2 (2.8)	73.2 (2.7)	73.6 (2.9)	73.5 (2.9)	73.3 (2.9)	73.3 (2.8)	73.9 (2.9)
Smoking, Pack-years, mean(SD)	17.6 (26.7)	15.1 (24.6)	19 (27.9)	19.0 (26.5)	12.2 (20.5)	18.6 (29)	21.9 (28.7)	15.0 (23.7)	16.6 (24.2)	20.8 (30.4)
Body mass index (kg/m2), mean (SD)	27.5 (4.9)	26.1 (4.0)	27.2 (4.5)	29.1 (5.4)	26.1 (4.0)	27.9 (4.5)	28.5 (5.5)	27.1 (5.0)	27.5 (4.8)	27.9 (4.8)
Gender, % Male	46	54	49	36	41	49	49	42	46	50
Race, % Caucasian	55	64	61	45	61	57	50	48	59	62
Site, % Memphis	50	46	50	50	46	50	53	53	46	49
Education %
Less than High School	26	22	24	30	23	26	29	28	23	27
High School	33	32	35	34	33	32	34	30	33	37
Post-secondary	41	45	41	36	44	42	37	41	44	36
Smoking Status, %
Never	45	50	44	42	52	45	39	48	45	43
Former	45	41	48	45	42	45	47	40	45	48
Current	10	9	8	13	7	10	14	12	10	9
Alcohol Consumption, %
None in Last Year	51	49	48	54	50	49	55	51	48	53
Less than Once per Week	21	22	21	20	22	22	19	21	21	22
1–7 Times per Week	20	22	23	19	23	20	18	20	24	17
More than 1 per Day	7	7	8	7	5	8	8	7	7	7
Medication Use, %
NSAIDs	22	22	20	22	25	22	20	20	24	24
Corticosteroids	4	3	4	5	2	4	5	4	4	4
Statins	12	14	13	13	12	12	13	11	12	15
Multivitamins	18	18	19	17	25	14	15	19	19	17
Comorbid Conditions, %
Cardiovascular Disease	54	49	52	62	46	54	60	49	51	60
Pulmonary Disease (COPD, Chronic Bronchitis, Emphysema)	13	12	13	14	10	12	16	13	12	13