Table 4.
Pre-Injury Diagnoses in Controls and Cases
| Diagnosis | NLP controls (n = 10,857) | NLP cases (n = 507) | p value vs. controls | Coded cases (n = 1142) | p value vs. controls |
|---|---|---|---|---|---|
| ADHD, n (%) | 227 (2.1) | 14 (2.8) | 0.39 | 24 (2.1) | 1 |
| Anxiety, n (%) | 560 (5.2) | 39 (7.7) | 0.02 | 112 (9.8) | 1.26E-10 |
| Depression, n (%) | 581 (5.4) | 36 (7.1) | 0.11 | 101 (8.8) | 1.74E-06 |
| Learning disability, n (%) | 129 (1.2) | 10 (2.0) | 0.17 | 19 (1.7) | 0.21 |
| Migraine, n (%) | 246 (2.3) | 35 (6.9) | 1.31E-10 | 117 (10.2) | 4.16E-50 |
| PTSD, n (%) | 100 (0.9) | 14 (2.8) | 1.25E-04 | 27 (2.4) | 1.18E-05 |
Diagnoses (see Supplementary Table S7) had to occur before the eligible mTBI in NLP patients, and before the first PCS billing code in coded patients.
NLP, natural language processing; ADHD, attention deficit hyperactive disorder; PTSD, post-traumatic stress disorder.