Table 1.
Baseline characteristics of the patients included in the study
All | No diabetes | Glucocorticoid induced diabetes | |
---|---|---|---|
Incidence (95% CI) | N = 171 100% |
n = 133 78% (72%–85%) |
n = 38, 4 patients treated with insulin 22% (16%–28%) |
Age, years, mean (min-max) | 64 (23–101) | 63 (23–101) | 66 (30–92) |
Sex (% female) | 50 | 51 | 45 |
Type of cancer | |||
• Primary brain tumor | 117 (68%) | 93 (70%) | 24 (63%) |
• Secondary brain tumor (metastasis) | 39 (23%) | 30 (23%) | 9 (24%) |
• Unclassified | 15 (9%) | 10 (7%) | 5 (13%) |
Performance status | |||
• 0 | 62 (36%) | 49 (37%) | 13 (34%) |
• 1 | 62 (36%) | 50 (38%) | 12 (32%) |
• 2 | 27 (16%) | 20 (15%) | 7 (18%) |
• 3 | 11 (7%) | 7 (5%) | 4 (10%) |
• 4 | 4 (2%) | 3 (2%) | 1 (3%) |
• Unclassified | 5 (3%) | 4 (3%) | 1 (3%) |
Smoking | |||
• Never smoker | 80 (47%) | 58 (44%) | 22 (58%) |
• Smoking now or previously | 87 (51%) | 71 (53%) | 16 (42%) |
• Missing | 4 (2%) | 4 (3%) | 0 (0%) |
Antihypertensive therapy | 47 (28%) | 33 (25%) | 14 (37%) |
Lipid-lowering therapy | 31 (18%) | 19 (14%) | 12 (32%) |
Symptomatic atherosclerosis | 14 (8%) | 10 (8%) | 4 (11%) |
Liver disease | 1 (1%) | 1 (1%) | 0 |
Pancreatic disease | 0 (0%) | 0 | 0 |
Number of glucose measurements in the 7 days observation period, median (IQR) | 10 (7–14) | 9 (6–12) | 15 (11–18) |
Cumulative prednisolone dose, mg, mean in the 7 days observation period (min-max) | 674 (150–2150) | 668 (150–2150) | 693 (475–1050) |