Table 3.
Univariate Cox regression models exploring predictors for drop out due to death
| Drop out due to death1 | |||
|---|---|---|---|
| Hazard Ratio | 95% Confidence Interval | P value | |
| Age in years | 1.09 | 1.03–1.14 | <.01 |
| Sex | |||
| male | 1.04 | 0.35–3.12 | .94 |
| female | 1.00 | ||
| Eloquent tumor location | |||
| yes | 1.81 | 0.59–5.56 | .30 |
| no | 1.00 | ||
| Surgery for recurrent tumor | |||
| yes | 2.59 | 0.85–7.9 | .09 |
| no | |||
| Karnofsky Index in percent | 0.92 | 0.88–0.96 | <.001 |
| Time since diagnosis in months | 0.99 | 0.97–1.0 | .09 |
| Value of Distress Thermometer | |||
| ≥ 6 | 1.35 | 0.44–4.2 | .60 |
| <6 | |||
| Selected EORTC QLQ-C30 and EORTC QLQ-BN20 scales | |||
| C30 Global Health Status/QoL | 0.99 | 0.96–1.01 | .28 |
| C30 Physical functioning | 0.98 | 0.96–1.00 | .04 |
| C30 Emotional functioning | 1.00 | 0.98–1.03 | .75 |
| C30 Cognitive functioning | 0.99 | 0.97–1.01 | .21 |
| BN20 Future uncertainty | 1.00 | 0.98–1.02 | 1.00 |
| BN20 Motor dysfunction | 1.02 | 1.00–1.04 | .02 |
| SCNS-SF34G scores | |||
| Physical and daily living needs | 0.99 | 0.95-1.01 | .34 |
| Psychological needs | 1.00 | 0.98–1.02 | .89 |
| Patient care and support needs | 0.99 | 0.96–1.02 | .56 |
| Health system and information needs | 0.97 | 0.93–1.01 | .10 |
| Sexuality needs | 0.97 | 0.92–1.02 | .19 |
1 The following factors were not tested for association with death-related drop out due to insufficient number of observation in the respective factor levels: living situation, WHO grade, and chemotherapy