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. Author manuscript; available in PMC: 2019 Jul 24.
Published in final edited form as: Pediatr Diabetes. 2019 Apr 15;20(4):408–413. doi: 10.1111/pedi.12845

TABLE 3.

R2 values for associations of HbA1c with C-peptide indices in multivariable models

Model Unadjusted
 BMI z-score and age included in model
Overall R2 of model Partial R2 P-value for partial R2 Overall R2 Partial R2 P-value for partial R2
(A) AUC C-peptide; 120/30 C-peptide 0.20 0.07, 0.12* 0.012, 0.002 0.22 0.12, 0.10* 0.001, 0.004
(B) Peak C-peptide; peak C-peptide after 60 minutes 0.20 0.10, 0.10* 0.003, 0.004 0.21 0.14, 0.08* <0.001, 0.013
(C) Early C-peptide; 120/30 C-peptide 0.25 0.14, 0.18** <0.001, <0.001 0.24 0.14, 0.17** <0.001, <0.001
(D) Early C-peptide; late C-peptide 0.20 0.09, 0.12** 0.005, 0.001 0.20 0.10, 0.13** 0.004, 0.001

Abbreviations: AUC, area under the curve; BMI, body mass index; HbA1c, hemoglobin A1c.

*

P ≤ 0.01.

**

P ≤ 0.001 for contribution to the R2 from the addition of the second term in each model.