Table 3.

Alternative RfD Calculations Using Toxicological and Epidemiological Studies

Dataset or Source(s)	Potential RfDs (mg/kg-day)
Draft Toxicological Review (Lehmann et al. 2004)	0.3
Alt 1) Applying a Database Deficiency adjustment of 3	0.1
Alt 2) Applying LOAEL to NOAEL adjustment (additional factor of 10)	0.03
Alt 3) Combining 1 and 2	0.01
Swan et al. 2005 with Marsee et al. 2006	0.001
Using UF of 1 for human variability
Swan et al. 2005 with Marsee et al. 2006	0.00001
Using UF of 110* for human variability

^*Upper end of range of human susceptibility from various sources as reported in Science and Decisions: Advancing Risk Assessment (NRC 2009).