Table 3.
Pathway | Gene | SNP ID | Location | Chr: | Position | MAF | MA | Sig. | OR |
---|---|---|---|---|---|---|---|---|---|
Clock | ARNTL2 | rs922270 | Intron | 12: | 27396218 | 0.155 | C | .033 | 1.869 |
Clock | CLOCK | rs3792603 | Intron | 4: | 55996815 | 0.215 | G | .059 | 1.599 |
Clock | PER1 | rs2253820 | Coding | 17: | 7988894 | 0.152 | A | .089 | .604 |
Clock | PER2 | rs934945 | Coding | 2: | 238819792 | 0.187 | A | .100 | .614 |
Clock | FBXL3 | rs700361 | Intron | 13: | 76497955 | 0.101 | C | .128 | .549 |
Clock | CLOCK | rs11932595 | Intron | 4: | 56018354 | 0.411 | G | .149 | 1.363 |
Clock | CLOCK | rs11931061 | Intron | 4: | 56033550 | 0.327 | G | .149 | .703 |
Clock | ARNTL2 | rs17497606 | Intron | 12: | 27385716 | 0.186 | T | .175 | 1.471 |
Clock | PER3 | rs707467 | Intron | 1: | 7784271 | 0.179 | G | .190 | .690 |
Clock | FBXL3 | rs9573983 | Intron | 13: | 76492516 | 0.066 | G | .191 | .561 |
Clock | PER3 | rs10462020 | Coding | 1: | 7803270 | 0.195 | G | .215 | 1.409 |
Clock | ARNTL2 | rs7300833 | Intron | 12: | 27441977 | 0.098 | G | .229 | .630 |
Clock | PER2 | rs10462023 | Intron | 2: | 238849320 | 0.407 | A | .300 | 1.259 |
Clock | PER3 | rs228642 | Intron | 1: | 7803233 | 0.412 | C | .353 | .806 |
Clock | ARNTL2 | rs11048980 | Intron | 12: | 27394814 | 0.091 | C | .370 | .721 |
Clock | PER1 | rs2585408 | 3’ Flanking | 17: | 7984478 | 0.423 | T | .439 | 1.186 |
Clock | ARNTL2 | rs2306073 | Intron | 12: | 27447104 | 0.322 | A | .441 | 1.196 |
Clock | ARNTL2 | rs2289709 | 3’ Flanking | 12: | 27464900 | 0.134 | A | .451 | 1.283 |
Clock | ARNTL2 | rs1471327 | Intron | 12: | 27420353 | 0.125 | T | .454 | .786 |
Clock | ARNTL2 | rs1443857 | Intron | 12: | 27436627 | 0.148 | A | .459 | 1.242 |
Inflammation | IL4 | rs2243300 | 5’ Flanking | 5: | 132031985 | 0.076 | T | .503 | .757 |
Clock | ARNTL2 | rs10842913 | Intron | 12: | 27460330 | 0.094 | A | .520 | 1.291 |
Clock | ARNTL2 | rs7306410 | Intron | 12: | 27416863 | 0.182 | C | .522 | 1.191 |
Clock | ARNTL2 | rs2587052 | Intron | 12: | 27460479 | 0.229 | T | .530 | 1.178 |
Clock | ARNTL2 | rs10506018 | Intron | 12: | 27387124 | 0.17 | G | .551 | .841 |
Clock | ARNTL2 | rs11048994 | Intron | 12: | 27422045 | 0.191 | A | .588 | .868 |
Clock | PER3 | rs697686 | Intron | 1: | 7790158 | 0.344 | A | .592 | .880 |
Clock | ARNTL2 | rs1037921 | Coding | 12: | 27444833 | 0.054 | C | .592 | 1.348 |
Clock | ARNTL2 | rs3751221 | Intron | 12: | 27429922 | 0.17 | C | .613 | 1.166 |
Clock | PER3 | rs10127838 | Intron | 1: | 7804367 | 0.224 | T | .614 | 1.135 |
Clock | CLOCK | rs1522113 | Intron | 4: | 56026528 | 0.053 | A | .617 | .787 |
Clock | ARNTL2 | rs1256955 | Intron | 12: | 27460292 | 0.192 | C | .629 | 1.143 |
Clock | ARNTL2 | rs11048977 | Intron | 12: | 27388716 | 0.198 | A | .656 | .886 |
Clock | CLOCK | rs9312661 | Intron | 4: | 56037083 | 0.378 | A | .716 | .920 |
Clock | PER3 | rs228682 | Intron | 1: | 7796286 | 0.411 | C | .785 | 1.063 |
Clock | ARNTL2 | rs4964058 | Intron | 12: | 27414033 | 0.469 | G | .817 | 1.052 |
Clock | PER3 | rs228729 | 5’ near gene | 1: | 7785635 | 0.332 | A | .823 | .951 |
Clock | PER2 | rs6431590 | Intron | 2: | 238829867 | 0.308 | G | .828 | .951 |
Clock | PER1 | rs2518023 | 5’ Flanking | 17: | 7997331 | 0.088 | A | .842 | .930 |
Clock | PER2 | rs4663868 | Intron | 2: | 238825830 | 0.08 | T | .856 | 1.071 |
Inflammation | IL4 | rs2243288 | Intron | 5: | 132045843 | 0.166 | G | .865 | .955 |
Clock | PER3 | rs228654 | Intron | 1: | 7837168 | 0.117 | T | .872 | 1.058 |
Clock | ARNTL2 | rs16931937 | Intron | 12: | 27439458 | 0.076 | C | .882 | .944 |
Clock | PER2 | rs2304673 | Intron | 2: | 238850661 | 0.148 | C | .901 | 1.039 |
Clock | FBXL3 | rs599115 | Intron | 13: | 76487726 | 0.322 | A | .941 | 1.016 |
Clock | ARNTL2 | rs4964059 | Intron | 12: | 27420486 | 0.354 | C | .953 | 1.013 |
Clock | ARNTL2 | rs4964060 | Intron | 12: | 27424634 | 0.414 | A | .964 | .990 |
Inflammation | IL4 | rs2243248 | 5’ Flanking | 5: | 132036543 | 0.059 | G | .974 | .985 |
Clock | PER3 | rs10462018 | Intron | 1: | 7802214 | 0.147 | T | 1.000 | 1.000 |
Clock | ARNTL2 | rs11048998 | Intron | 12: | 27437644 | 0.133 | C | 1.000 | 1.000 |
Chr, chromosome; SNP, single nucleotide polymorphism; MA, minor allele; MAF, minor allele frequency; Sig., significance