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. Author manuscript; available in PMC: 2019 Jul 24.
Published in final edited form as: Cell Rep. 2019 Jul 9;28(2):368–381.e6. doi: 10.1016/j.celrep.2019.06.025

Figure 2. Estradiol Maintains the Satellite Cell Pool and Accelerates Recovery of Strength.

Figure 2.

(A) Representative FACS plots of cells isolated from TA muscles of Ovx mice without (n = 3) and with 17μ-estradiol treatment (Ovx+E2; n = 4).

(B) Total number of satellite cells.

(C) TA muscle mass.

(D) Total number of satellite cells relative to TA muscle mass.

(E) Maximal isometric torque (i.e., strength) expressed relative to pre-injury torque in Ovx mice without (Ovx+Placebo; n = 6) or with 17β-estradiol treatment (Ovx+E2; n = 8) following repeated injuries to TA muscle.

*p < 0.05 and **p < 0.005 by Student’s t tests (A–D) and Holm-Sidak post hoc (E).