Fig. 4.

Flow diagram providing an indication of turnaround times (in working days) for several of the techniques described in this review article. These are the usual turnaround times of the authors’ laboratory or institution. Turnaround times may vary from laboratory to laboratory, for example, depending on the possibility of performing certain steps overnight.

FISH indicates fluorescent in situ hybridization; MS-MLPA, methylation-specific multiplex ligation-dependent probe amplification; MSP, methylation-specific polymerase chain reaction; NaBi, sodium bisulfite; NGS, next-generation sequencing; PCR, polymerase chain reaction; SNP, single-nucleotide polymorphism.