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. 2018 Oct 5;6(3):163–178. doi: 10.1093/nop/npy037

Table 3.

Ongoing Clinical Trials of Conventional Radio- and Chemotherapy in Atypical Teratoid/Rhabdoid Tumors

Clinicaltrials. gov ID Recruitment Status Phases Intervention
NCT00003141 Completed Phase 1 HSCT; carboplatin, cisplatin, cyclophosphamide, etoposide, thiotepa, vincristine
NCT00007813 Unknown Phase 1 HSCT; carboplatin, cyclophosphamide, etoposide
NCT00047177 Completed Phase 2 Oxaliplatin
NCT00053118 Completed Phase 1 HSCT; carboplatin
NCT00084838 Completed Phase 2 Radiation; cisplatin, cyclophosphamide, cytarabine, dexrazoxane, doxorubicin, etoposide, methotrexate, temozolomide, hydrocortisone, vincristine, dactinomycin
NCT00085202 Active, not recruiting Phase 3 HSCT; radiation; cisplatin, cyclophosphamide, vincristine
NCT00100880 Completed Phase 1 Lenalidomide
NCT00112619 Terminated Phase 1 Topotecan
NCT00138216 Completed Phase 1 Irinotecan, temoxolomide, vincristine
NCT00392886 Unknown Phase 3 HSCT; radiation; carboplatin, cisplatin, cyclophosphamide, etoposide, methotrexate, temozolomide, thiotepa, vincristine
NCT00602667 Active, not recruiting Phase 2 Risk-stratified combination of methotrexate, vincristine, cisplatin, cyclophosphamide, carboplatin, etoposide, topotecan, erlotinib, vinblastine
NCT00623077 Terminated Phase 1 Radiation; busulfan, etoposide, ifosfamide, melphalan, thiotepa
NCT00653068 Active, not recruiting Phase 3 HSCT; methotrexate, etoposide, cyclophosphamide, cisplatin, carboplatin, thiotepa, vincristine
NCT00983398 Recruiting Phase 1/2 Carboplatin, mannitol, melphalan
NCT01331135 Active, not recruiting Phase 1 Sirolimus
NCT01505569 Recruiting Phase 1 HSCT; radiation; etoposide, busulfan, melphalan, thiotepa, carboplatin, paclitaxel
NCT01737671 Completed Phase 1 IT methotrexate
NCT02684071 Recruiting Phase 2 IT methotrexate, topotecan, cyclophosphamide

Abbreviations: HSCT, hematopoietic stem cell transplantation; ID, identification; IT, intrathecal.