Figure 3.

Endocrine pancreas morphometry of 15-wk-old lean and GDM offspring. (A) Number of islets per pancreas tissue area. (B) Islet area per pancreas tissue area. (C) β-Cell fraction. (D) Number of β-cells per islet area. (E) α-Cell fraction. (F) Number of α-cells per islet area. Data are mean ± SEM (n = 6 by group). The HFS diet included 45% fat (4.73 kcal/g); the LF diet included 10% fat (3.85 kcal/g). ^aP < 0.05, Lean-LF vs Lean-HFS; ^bP < 0.05, Lean-HFS vs GDM-LF; ^cP < 0.05, Lean-HFS vs GDM-HFS using a two-way ANOVA followed by a Bonferroni posttest.